To build and run projects for Chrome OS, you need to set up a Chrome OS development environment. Android and Chrome OS use the same Unity environment, so you can use the Android instructions to set up your development environment for Chrome OS. For information on how to set up an Android environment, refer to Android Environment Setup.
When you develop applications for Chrome OS, you can’t debug a Chrome OS application using a USB connection. As a result, you must connect to the Chrome OS device over Wifi or Ethernet using Android Debug Bridge (adb). For more information, refer to ‘Connect to a device over Wi-Fi (Android 11+).’.